Rasio neutrofil limfosit (RNL), mean platelet volume (MPV), serta red cell distribution width (RDW) sebagai prediktor tunggal sepsis neonatorum awitan dini (SNAD) di RSUD Wangaya Kota Denpasar, Bali

Background: Sepsis is still a serious world health threat, especially in developing countries, including Indonesia. Blood culture examination as the gold standard for diagnosis has several drawbacks, thus encouraging clinicians to find new markers with shorter times and affordable costs. This study examines relationship between RNL, MPV RDW early-onset neonatal sepsis (EONS) at Wangaya Hospital, Denpasar City. Methods: cross-sectional analytic observational using consecutive sampling method was carried out by collecting medical record data neonates risk who were treated City from January 2020 September 2021. The cut off values determined receiver-operating characteristic curve. (ROC). Chi-square analysis multivariate logistic regression performed determine significant relationship. Results: Of 110 sample subjects, 57 subjects (47.5%) had of SNAD. results bivariate analysis, RNL value 2.23 (p<0.001), 9.95 fL 16.15% (p<0.001) associated EONS. showed that (OR=3.32, p=0.012), (OR=3.83, p=0.004), (OR=3.47, p=0.006) single predictors Conclusion: neutrophil lymphocyte ratio (RNL), red cell distribution width (RDW), mean platelet volume (MPV) independent predictor (SNAD). Latar Belakang: saat ini masih merupakan ancaman kesehatan dunia yang serius, terutama di negara berkembang, termasuk Pemeriksaan kultur darah sebagai baku emas memiliki beberapa kelemahan, sehingga mendorong klinisi untuk menemukan penanda baru dengan waktu pemeriksaan lebih singkat dan biaya terjangkau. Studi meneliti hubungan serta neonatorum awitan dini (SNAD) RSUD Wangaya, Kota Denpasar. Metode: Penelitian observasional analitik potong lintang menggunakan metode dilakukan mengumpulkan rekam medis neonatus resiko dirawat dari Januari hingga Nilai ditentutkan kurva Analisis chi-square regresi logistik multivariat mengetahui bermakna. Hasil: Dari subjek sampel, sebesar (47,5%) Hasil analisis bivariat, nilai (p<0,001), 9,95 16,15% (p<0,001) berhubungan multivariat, menunjukkan (OR=3,32, p=0,012), (OR=3,83, p=0,004), (OR=3,47, p=0,006) prediktor tunggal kejadian Simpulan: rasio neutrofil limfosit